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Tumor Necrosis Factor Receptor Associated Periodic Syndrome
Medications for Tumor Necrosis Factor Receptor Associated Periodic Syndrome
Other names: Familial Hibernian Fever; TNF Receptor Associated Periodic Syndrome; TRAPS
About Tumor Necrosis Factor Receptor Associated Periodic Syndrome: Tumor necrosis factor receptor associated periodic syndrome (TRAPS) is an inheritable autosomal dominant disease that`s characterized by episodes of fevers. The frequency and duration of these episodes varies among individuals. In addition to fever associated symptoms are pain, rash, nausea conjunctivitis, along with pain, abdominal pain. Have a worse prognosis compared to some other folks. TRAPS is is brought on by a mutation at the TNFRSF1A gene which causes the protein tumor necrosis factor receptor 1 (TNFR1) being faulty) TNFR1 is within membrane cells also has an important role in signalling and triggering apoptosis and inflammation, yet in TRAPS the faulty TNFR1 is trapped inside the cells and also constantly activates inflammation pathways which leads to excessive inflammation.
Drugs Used to Treat Tumor Necrosis Factor Receptor Associated Periodic Syndrome
The following set of medications are utilized at the treating this condition, or somehow associated with.
| Drug name | Rx / OTC | Pregnancy | CSA | Alcohol | Reviews | Rating | Popularity |
|---|---|---|---|---|---|---|---|
| canakinumab | Rx | C | N | Insert review | 0.0 | ||
Generic title: canakinumab systemic Brand title: Ilaris Drug class: interleukin inhibitors For consumers: dosage, interactions, For specialists: Az Drug Truth, AHFS DI Monograph | |||||||
| Ilaris | Rx | C | N | Insert review | 0.0 | ||
Generic title: canakinumab systemic Drug class: interleukin inhibitors For consumers: dosage, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information | |||||||
Legend
| Rx | Prescription Only |
|---|---|
| OTC | Over the Counter |
| Rx/OTC | Prescription or Over the Counter |
| Off Label | This drug may well not be accepted by the FDA for treating this condition. |
| Pregnancy Category | |
|---|---|
| A | Adequate and well-controlled studies have failed to demonstrate a risk to the embryo within the first trimester of pregnancy (also there is no evidence of risk in later trimesters). |
| B | Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no sufficient and well-controlled studies in elderly women. |
| C | Animal research studies have demonstrated a negative effect in the fetus and there are no sufficient and well-controlled studies in humans, but potential benefits may warrant used in pregnant women despite potential risks. |
| D | there was positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant used in pregnant women despite potential risks. |
| X | Studies in animals or humans have demonstrated fetal abnormalities or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and also the risks involved with used in elderly women obviously outweigh potential gains. |
| N | FDA have not classified the drug. |
| Controlled Substances Act (CSA) Program | |
|---|---|
| N | Is not subject to the Controlled Substances Act. |
| 1 | includes a higher potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision. |
| Two | includes a higher potential for abuse. Features a currently accepted medical use with severe restrictions or a currently accepted medical use in treatment in the United States. Abuse may cause acute physical or psychological dependency. |
| 3 | Has a possibility for abuse less than those in schedules 1 and two. Features a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
| 4 | includes a minimal potential for abuse in accordance with those in program 3. It`s a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in program 3. |
| 5 | includes a minimal potential for abuse in accordance with those in program 4. Features a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in program 4. |
| Infection | |
|---|---|
| X | Interacts with Alcohol. |
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Further advice
Always ask your healthcare provider to make sure the information applies to your circumstances.
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